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CF60
Recombinant Human Cystathionine gamma-lyase/CTH
10ug
760
684
现货
国产
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CF60
Recombinant Human Cystathionine gamma-lyase/CTH
50ug
2280
2052
现货
国产
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CF60
Recombinant Human Cystathionine gamma-lyase/CTH
500ug
12320
11088
现货
国产
-
CF60
Recombinant Human Cystathionine gamma-lyase/CTH
1mg
17600
15840
现货
国产
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Catalog# CF60 Source E.coli Description Recombinant Human Cystathionine Gamma-Lyase/CTH is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser405) of Human CTH. Names Cystathionine Gamma-Lyase, Cysteine-Protein Sulfhydrase, Gamma-Cystathionase, CTH Accession # P32929 Formulation Supplied as a 0.2 μm filtered solution of PBS, pH 7.4 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence GHMQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRS GNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEF GLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSP YFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRG LKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQ HAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLE DLDQALKAAHPPSGSHSBackground Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.