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CE63
Recombinant Human D-amino-acid oxidase/DAO
10ug
1200
1080
现货
国产
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CE63
Recombinant Human D-amino-acid oxidase/DAO
50ug
3520
3168
现货
国产
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CE63
Recombinant Human D-amino-acid oxidase/DAO
500ug
12320
11088
现货
国产
-
CE63
Recombinant Human D-amino-acid oxidase/DAO
1mg
17600
15840
现货
国产
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Catalog# CE63 Source E.coli Description Recombinant Human D-Amino-Acid Oxidase/DAO is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Leu347) of Human DAO fused with a 6His tag at the N-terminus. Names D-Amino-Acid Oxidase, DAAO, DAMOX, DAO Accession # P14920 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, 2mM EDTA, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTT DVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDT VLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGA DVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGG IFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEV IHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHLBackground D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxide. D-amino-acid oxidase regulates the level of the neuromodulator D-serine in the brain, has a high activity towards D-DOPA and contributes to dopamine synthesis. D-amino-acid oxidase could act as a detoxifying agent which removes D-amino acids accumulated during aging. It also acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups.
