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C125
Recombinant Human Defensin (β-Defensin 1)/DEFB1
10ug
840
756
现货
国产
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C125
Recombinant Human Defensin (β-Defensin 1)/DEFB1
50ug
2520
2268
现货
国产
-
C125
Recombinant Human Defensin (β-Defensin 1)/DEFB1
500ug
12320
11088
现货
国产
-
C125
Recombinant Human Defensin (β-Defensin 1)/DEFB1
1mg
17600
15840
现货
国产
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Catalog# C125 Source E.coli Description Recombinant Human β-Defensin 1/DEFB1 is produced with our E. coli expression system. The target protein is expressed with sequence (Gly22-Lys68) of Human DEFB1. Names Beta-Defensin 1, BD-1, hBD-1, Defensin Beta 1, DEFB1, BD1, HBD1 Accession # P60022 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 130mM NaCl, pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence GNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCKBackground β-Defensin 1 (DEFB1) is a member of the β-defensin family, which is highly expressed by epithelial cells. β-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in β-Defensin-1 contribute to asthma diagnosis, with apparent gender-specific effects in human. β-defensin 1 may also play a role in the pathogenesis of severe sepsis. In addition, β-defensin 1 is associated with induction profiles in gingival keratinocytes.