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CF06
Recombinant Human Deoxycytidine kinase/DCK
10ug
760
684
现货
国产
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CF06
Recombinant Human Deoxycytidine kinase/DCK
50ug
2280
2052
现货
国产
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CF06
Recombinant Human Deoxycytidine kinase/DCK
500ug
12320
11088
现货
国产
-
CF06
Recombinant Human Deoxycytidine kinase/DCK
1mg
17600
15840
现货
国产
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Catalog# CF06 Source E.coli Description Recombinant Human Deoxycytidine Kinase/DCK is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Leu260) of Human DCK fused with a 6His tag at the N-terminus. Names Deoxycytidine Kinase, dCK, DCK Accession # P27707 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris, pH 7.5 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRGSMATPPKRSCPSFSASSEGTRIKKISIEGNIA AGKSTFVNILKQLCEDWEVVPEPVARWCNVQSTQDEFEELTMSQKNGGNVLQMMYEKPERWSFTF QTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESECMNETEWTIYQDWHDW MNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFD YLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTLBackground Deoxycytidine Kinase (DCK) is a member of the DCK/DGK family. DCK exists as a homodimer and is localized to the nucleus. DCK is required for the phosphorylation of the deoxyribonucleosides deoxycytidine (dC), deoxyguanosine (dG), and deoxyadenosine (dA). DCK has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. In addition, DCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents. DCK is clinically important because of its relationship to drug resistance and sensitivity.
