产品中心
-
产品货号
产品名称
规格
销售价
会员价
货期
产地
订购
-
C852
Recombinant Human Dihydropteridine reductase/QDPR
10ug
840
756
现货
国产
-
C852
Recombinant Human Dihydropteridine reductase/QDPR
50ug
2520
2268
现货
国产
-
C852
Recombinant Human Dihydropteridine reductase/QDPR
500ug
12320
11088
现货
国产
-
C852
Recombinant Human Dihydropteridine reductase/QDPR
1mg
17600
15840
现货
国产
- 产品简介
- 使用说明
- 相关产品
- 参考文献
- 购买咨询
Catalog# C852 Source HEK293 Description Recombinant Human Dihydropteridine Reductase/QDPR is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Phe244) of Human QDPR fused with a polyhistidine tag at the C-terminus. Names Dihydropteridine Reductase, HDHPR, Quinoid Dihydropteridine Reductase, QDPR, DHPR Accession # P09417 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl,pH8.0 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MAAAAAAGEARRVLVYGGRGALGSRCVQAFRARNWWVASVDVVENEEASASIIVKMTDSFTEQAD QVTAEVGKLLGEEKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTISSHLATKHLKEGG LLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPPGAAAIAVLPVTLDTPMNRKSMP EADFSSWTPLEFLVETFHDWITGKNRPSSGSLIQVVTTEGRTELTPAYFVDHHHHHHBackground Dihydropteridine reductase, also known as HDHPR and Quinoid dihydropteridine reductase, QDPR and DHPR, belongs to the short-chain dehydrogenases/reductases (SDR) family. QDPR exists as a homodimer. QDPR is part of the pathway that recycles a substance called tetrahydrobiopterin, also known as BH4 and tryptophan hydroxylases. The regeneration of this substance is critical for the proper processing of several other amino acids in the body. Tetrahydrobiopterin also helps produce certain chemicals in the brain called neurotransmitters, which transmit signals between nerve cells. Defects in QDPR are the cause of BH4-deficient hyperphenylalaninemia type C (HPABH4C) which is a rare autosomal recessive disorder and is lethal.