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CD79
Recombinant Human CD358/DR6/TNFRSF21
10ug
760
684
现货
国产
-
CD79
Recombinant Human CD358/DR6/TNFRSF21
50ug
2000
1800
现货
国产
-
CD79
Recombinant Human CD358/DR6/TNFRSF21
500ug
12320
11088
现货
国产
-
CD79
Recombinant Human CD358/DR6/TNFRSF21
1mg
17600
15840
现货
国产
-
CD79
Recombinant Human DR6/TNFRSF21/CD358
10ug
760
684
现货
国产
-
CD79
Recombinant Human DR6/TNFRSF21/CD358
50ug
2000
1800
现货
国产
-
CD79
Recombinant Human DR6/TNFRSF21/CD358
500ug
12320
11088
现货
国产
-
CD79
Recombinant Human DR6/TNFRSF21/CD358
1mg
17600
15840
现货
国产
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Catalog# CD79 Source Human Cells Description Recombinant Mouse Tumor necrosis factor receptor superfamily member 21/DR6/TNFRSF21 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln42-His349) of Mouse TNFRSF21 fused with a FC-6His tag at the C-terminus. Names Tumor necrosis factor receptor superfamily member 21 ，Death receptor 6 ，Tnfrsf21, CD358; BM-018 Accession # Q9EPU5 Formulation Lyophilized from a 0.2 μm filtered solution of PBS，pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence QPEQKTLSLPGTYRHVDRTTGQVLTCDKCPAGTYVSEHCTNMSLRVCSSCPAGTFTRHENGIERC HDCSQPCPWPMIERLPCAALTDRECICPPGMYQSNGTCAPHTVCPVGWGVRKKGTENEDVRCKQC ARGTFSDVPSSVMKCKAHTDCLGQNLEVVKPGTKETDNVCGMRLFFSSTNPPSSGTVTFSHPEHM ESHDVPSSTYEPQGMNSTDSNSTASVRTKVPSGIEEGTVPDNTSSTSGKEGTNRTLPNPPQVTHQ QAPHHRHILKLLPSSMEATGEKSSTAIKAPKRGHPRQNAHKHFDINEHVDDIEGRMDEPKSCDKT HTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAK TKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPP SREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQ QGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH*Background Tumor necrosis factor receptor superfamily member 21(DR6) is a single-pass type I membrane protein and contains 1 death domain and 4 TNFR-Cys repeats. The protein may activate NF-kappa-B and promote apoptosis and it may activate JNK and be involved in T-cell differentiation.It is required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).