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CF59
Recombinant Human E3 ubiquitin-protein ligase parkin/PARK2/PRKN
10ug
1200
1080
现货
国产
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CF59
Recombinant Human E3 ubiquitin-protein ligase parkin/PARK2/PRKN
50ug
3520
3168
现货
国产
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CF59
Recombinant Human E3 ubiquitin-protein ligase parkin/PARK2/PRKN
500ug
13440
12096
现货
国产
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CF59
Recombinant Human E3 ubiquitin-protein ligase parkin/PARK2/PRKN
1mg
19200
17280
现货
国产
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Catalog# CF59 Source E.coli Description Recombinant Human Parkinson Juvenile Disease Protein 2/PARK2 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Lys387) of Human PARK2 fused with a 6His tag at the C-terminus. Names E3 Ubiquitin-Protein Ligase Parkin, Parkinson Juvenile Disease Protein 2, Parkinson Disease Protein 2, PARK2, PRKN Accession # O60260-5 Formulation Supplied as a 0.2 μm filtered solution of PBS, 20% Glycerol, 2mM DTT, pH 7.4 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Biological Activity IN STOCK Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MIVFVRFNSSHGFPVEVDSDTSIFQLKEVVAKRQGVPADQLRVIFAGKELRNDWTVQNCDLDQQS IVHIVQRPWRKGQEMNATGGDDPRNAAGGCEREPQSLTRVDLSSSVLPGDSVGLAVILHTDSRKD SPPAGSPAGRSIYNSFYVYCKGPCQRVQPGKLRVQCSTCRQATLTLTQGPSCWDDVLIPNRMSGE CQSPHCPGTSAEFFFKCGAHPTSDKETSVALHLIATNSRNITCITCTDVRSPVLVFQCNSRHVIC LDCFHLYCVTRLNDRQFVHDPQLGYSLPCVGTGDTVVLRGALGGFRRGVAGCPNSLIKELHHFRI LGEEQYNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGYGQRRTKLEH HHHHHBackground E3 Ubiquitin-Protein Ligase Parkin (PARK2) belongs to the RBR family and Parkin subfamily. PARK2 is expressed in the heart, testis, skeletal muscle, with high expression levels found in the brain including the substantianigra. PARK2 is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. The mutations of gene encoding this protein will result in Parkinson disease and autosomal recessive juvenile Parkinson disease.