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C113
Recombinant Human CCL26/Eotaxin-3(24-94)
10ug
936
842.4
现货
国产
-
C113
Recombinant Human CCL26/Eotaxin-3(24-94)
50ug
2800
2520
现货
国产
-
C113
Recombinant Human CCL26/Eotaxin-3(24-94)
500ug
9840
8856
现货
国产
-
C113
Recombinant Human CCL26/Eotaxin-3(24-94)
1mg
14080
12672
现货
国产
-
C113
Recombinant Human Eotaxin-3/CCL26(24-94)
10ug
936
842.4
现货
国产
-
C113
Recombinant Human Eotaxin-3/CCL26(24-94)
50ug
2800
2520
现货
国产
-
C113
Recombinant Human Eotaxin-3/CCL26(24-94)
500ug
9840
8856
现货
国产
-
C113
Recombinant Human Eotaxin-3/CCL26(24-94)
1mg
14080
12672
现货
国产
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Catalog# C113 Source E.coli Description Recombinant Human C-C Motif Chemokine 26/CCL26 (24-94) is produced with our E. coli expression system. The target protein is expressed with sequence (Thr24-Leu94) of Human CCL26. Names C-C Motif Chemokine 26, CC Chemokine IMAC, Eotaxin-3, Macrophage Inflammatory Protein 4-Alpha, MIP-4-Alpha, Small-Inducible Cytokine A26, Thymic Stroma Chemokine-1, TSC-1, CCL26, SCYA26 Accession # Q9Y258 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris, 1mM EDTA, 20% Glycerol, pH 9.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MTRGSDISKTCCFQYSHKPLPWTWVRSYEFTSNSCSQRAVIFTTKRGKKVCTHPRKKWVQKYISL LKTPKQLBackground Chemokine Ligand 26 protein (CCL26) is a novel small cytokine belonging to the CC chemokine family which is involved in immunoregulatory and inflammatory processes. CCL26 is constitutively expressed in thymus, but only transiently expressed in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for CCL26 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant CCL26 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, CCL26 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. CCL26 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.