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C114

Recombinant Human CCL26/Eotaxin-3(27-94)

10ug

1024

921.6

现货

国产

C114

Recombinant Human CCL26/Eotaxin-3(27-94)

50ug

3080

2772

现货

国产

C114

Recombinant Human CCL26/Eotaxin-3(27-94)

500ug

12320

11088

现货

国产

C114

Recombinant Human CCL26/Eotaxin-3(27-94)

1mg

17600

15840

现货

国产

C114

Recombinant Human Eotaxin-3/CCL26(27-94)

10ug

1024

921.6

现货

国产

C114

Recombinant Human Eotaxin-3/CCL26(27-94)

50ug

3080

2772

现货

国产

C114

Recombinant Human Eotaxin-3/CCL26(27-94)

500ug

12320

11088

现货

国产

C114

Recombinant Human Eotaxin-3/CCL26(27-94)

1mg

17600

15840

现货

国产

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  • Catalog# C114
    Source E.coli
    Description Recombinant Human C-C Motif Chemokine 26/CCL26 (27-94) is produced with our E. coli expression system. The target protein is expressed with sequence (Ser27-Leu94) of Human CCL26.
    Names C-C Motif Chemokine 26, CC Chemokine IMAC, Eotaxin-3, Macrophage Inflammatory Protein 4-Alpha, MIP-4-Alpha, Small-Inducible Cytokine A26, Thymic Stroma Chemokine-1, TSC-1, CCL26, SCYA26
    Accession # Q9Y258
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    MSDISKTCCFQYSHKPLPWTWVRSYEFTSNSCSQRAVIFTTKRGKKVCTHPRKKWVQKYISLLKT PKQL
    Background Chemokine (C C Motif) Ligand 26 (CCL26) is a novel small cytokine belonging to the CC chemokine family, which involved in immunoregulatory and inflammatory processes. CCL26 is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. Eotaxin-3/CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for Eotaxin-3 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant Eotaxin-3 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, Eotaxin-3 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. Eotaxin-3 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.