产品中心

产品货号

产品名称

规格

销售价

会员价

货期

产地

订购

CD11

Recombinant Human Ephrin type-B receptor 1/EPHB1

10ug

1200

1080

现货

国产

CD11

Recombinant Human Ephrin type-B receptor 1/EPHB1

50ug

3520

3168

现货

国产

CD11

Recombinant Human Ephrin type-B receptor 1/EPHB1

500ug

13440

12096

现货

国产

CD11

Recombinant Human Ephrin type-B receptor 1/EPHB1

1mg

19200

17280

现货

国产

  • 产品简介
  • 使用说明
  • 相关产品
  • 参考文献
  • 购买咨询
  • Catalog# CD11
    Source Human Cells
    Description Recombinant Human Ephrin Type-B Receptor 1/EphB1 is produced by our mammalian expression system. The target protein is expressed with sequence (Met18-Pro540) of Human EPHB1 fused with a FC tag at the C-terminus.
    Names Ephrin Type-B Receptor 1, ELK, EPH Tyrosine Kinase 2, EPH-Kike Kinase 6, EK6, hEK6, Neuronally-Expressed EPH-Related Tyrosine Kinase, NET, Tyrosine-Protein Knase Receptor EPH-2, EPHB1, ELK, EPHT2, HEK6, NET
    Accession # P54762
    Formulation Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MEETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFINRRGA HRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVDTIAADESFS QVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPSIVQNFAVFPETMTG AESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKPGYEPENSVACKACPAGTFKA SQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFDPPEVACTSVPSGPRNVISIVNETSIILEW HPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVEFVPRQLGLTECRVSISSLWAHTPYTFDIQ AINGVSSKSPFPPQHVSVNITTNQAAPSTVPIMHQVSATMRSITLSWPQPEQPNGIILDYEIRYY EKEHNEFNSSMARSQTNTARIDGLRPGMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDYKSELRE QLPVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSH EDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIE KTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVL DSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    Background Ephrin Type-B Receptor 1 (EPHB1) is a single-pass type I membrane protein that belongs to the Ephrin-B family of receptor tyrosine kinases involved in the development of embryonic nervous and vascular systems. EPHB1 contains two fibronectin type-III domains, one protein kinase domain and one Sterile Alpha Motif (SAM)domain. EPHB1 is able to stimulate fibroblast motility on extracellular matrix in a kinase-dependent manner, which is also correlated with its association with Grb7, an adaptor molecule implicated in the regulation of cell migration. It binds to Ephrin-B1, Ephrin-B2 and Ephrin-B3. EPHB1 plays an important roles in diverse biological processes including nervous system development, angiogenesis, and neural synapsis formation and maturation and may be involved in cell-cell interactions in the nervous system.