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C656

Recombinant Human Epididymal secretory protein E1/NPC2

10ug

1200

1080

现货

国产

C656

Recombinant Human Epididymal secretory protein E1/NPC2

50ug

3520

3168

现货

国产

C656

Recombinant Human Epididymal secretory protein E1/NPC2

500ug

12320

11088

现货

国产

C656

Recombinant Human Epididymal secretory protein E1/NPC2

1mg

17600

15840

现货

国产

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  • Catalog# C656
    Source HEK293
    Description Recombinant Human Epididymal Secretory Protein E1/NPC2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu20-Leu151) of Human NPC2 fused with a polyhistidine tag at the C-terminus.
    Names Epididymal Secretory Protein E1, Human Epididymis-Specific Protein 1, He1, Niemann-Pick Disease Type C2 Protein, NPC2, HE1
    Accession # P61916
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    EPVQFKDCGSVDGVIKEVNVSPCPTQPCQLSKGQSYSVNVTFTSNIQSKSSKAVVHGILMGVPVP FPIPEPDGCKSGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQDDKNQSLFCWEIPVQIVS HLVDHHHHHH
    Background Epididymal Secretory Protein E1 (NPC2) is a secreted protein that belongs to the NPC2 family. NPC2 is involved in the regulation of the lipid composition of sperm membranes during the maturation in the epididymis. NPC2 may regulate the transport of cholesterol through the late endosomal/lysosomal system. Defects in NPC2 are the cause of Niemann-Pick disease type C2, which affects the viscera and the central nervous system.