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CH03

Recombinant Human CD340/Erbb2

10ug

760

684

现货

国产

CH03

Recombinant Human CD340/Erbb2

50ug

2000

1800

现货

国产

CH03

Recombinant Human CD340/Erbb2

500ug

12320

11088

现货

国产

CH03

Recombinant Human CD340/Erbb2

1mg

17600

15840

现货

国产

CH03

Recombinant Human ERBB2/CD340

10ug

760

684

现货

国产

CH03

Recombinant Human ERBB2/CD340

50ug

2000

1800

现货

国产

CH03

Recombinant Human ERBB2/CD340

500ug

12320

11088

现货

国产

CH03

Recombinant Human ERBB2/CD340

1mg

17600

15840

现货

国产

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  • Catalog# CH03
    Source E.coli
    Description Recombinant Rat Receptor tyrosine-protein kinase erbB-2/Erbb2 is produced with our E. coli expression system. The target protein is expressed with sequence (Ala67-Val323) of Rat Erbb2 fused with a 6His tag at the C-terminus.
    Names Receptor tyrosine-protein kinase erbB-2, Epidermal growth factor receptor-related protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, p185erbB2, p185neu, CD340, ERBB2.
    Accession # P06494
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl, 4M Urea, pH 8.0
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MANASLSFLQDIQEVQGYMLIAHNQVKRVPLQRLRIVRGTQLFEDKYALAVLDNRDPQDNVAAST PGRTPEGLRELQLRSLTEILKGGVLIRGNPQLCYQDMVLWKDVFRKNNQLAPVDIDTNRSRACPP CAPACKDNHCWGESPEDCQILTGTICTSGCARCKGRLPTDCCHEQCAAGCTGPKHSDCLACLHFN HSGICELHCPALVTYNTDTFESMHNPEGRYTFGASCVTTCPYNYLSTEVGSCTLVCPPNNQEVHH HHHH*
    Background 'ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpression of ErbB2 has been reported associated with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate and ovarian cancers. Rat ERBB2 is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. ErbB2 mediates signalling pathways which involve mitogen-activated protein kinase and phosphatidylinositol-3 kinase, this receptor plays a key role in development, cell proliferation and differentiation.'

     

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