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C139
Recombinant Human FBPase 1/FBP1/Fructose-1,6-bisphosphatase 1
10ug
640
576
现货
国产
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C139
Recombinant Human FBPase 1/FBP1/Fructose-1,6-bisphosphatase 1
50ug
1760
1584
现货
国产
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C139
Recombinant Human FBPase 1/FBP1/Fructose-1,6-bisphosphatase 1
500ug
12320
11088
现货
国产
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C139
Recombinant Human FBPase 1/FBP1/Fructose-1,6-bisphosphatase 1
1mg
17600
15840
现货
国产
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Catalog# C139 Source E.coli Description Recombinant Human Fructose-1,6-Bisphosphatase 1/FBPase 1 is produced with our E. coli expression system. The target protein is expressed with sequence (Ala2-Gln338) of Human FBPase 1. Names Fructose-1,6-Bisphosphatase 1, FBPase 1, D-Fructose-1,6-Bisphosphate 1-Phosphohydrolase 1, FBP1, FBP Accession # P09467 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, 1mM DTT, 1mM EDTA, 20% Glycerol, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MADQAPFDTDVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTN VTGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCL VSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFI LVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYG GIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDV LEFLKVYEKHSAQVEHHHHHHBackground Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.