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CB85

Recombinant Human CD16b/Fc gamma RIIIB

10ug

760

684

现货

国产

CB85

Recombinant Human CD16b/Fc gamma RIIIB

50ug

2000

1800

现货

国产

CB85

Recombinant Human CD16b/Fc gamma RIIIB

500ug

12320

11088

现货

国产

CB85

Recombinant Human CD16b/Fc gamma RIIIB

1mg

17600

15840

现货

国产

CB85

Recombinant Human Fc-gamma RIIIB/CD16b

10ug

760

684

现货

国产

CB85

Recombinant Human Fc-gamma RIIIB/CD16b

50ug

2000

1800

现货

国产

CB85

Recombinant Human Fc-gamma RIIIB/CD16b

500ug

12320

11088

现货

国产

CB85

Recombinant Human Fc-gamma RIIIB/CD16b

1mg

17600

15840

现货

国产

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  • Catalog# CB85
    Source HEK293
    Description Recombinant Human Fc gamma RIIIB/CD16b is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Thr20­Gln208) of Human FCGR3B fused with a FC-6His tag at the C-terminus.
    Names Low affinity immunoglobulin gamma Fc region receptor III-B, Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B.
    Accession # O75015
    Formulation Lyophilized from a 0.2 μm filtered solution of PBS
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    TEDLPKAVVFLEPQWYSVLEKDSVTLKCQGAYSPEDNSTQWFHNESLISSQASSYFIDAATVNDS GEYRCQTNLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDPIHLRCHSWKNTALHKVTYLQNGKDRK YFHHNSDFHIPKATLKDSGSYFCRGLVGSKNVSSETVNITITQGLAVSTISSFSPPGYQVDDIEG RMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNW YVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQ PREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLY SKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGKHHHHHH
    Background Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.