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CF28

Recombinant Human FIS1/Mitochondrial fission 1 protein/TTC11/CGI-135

10ug

360

324

现货

国产

CF28

Recombinant Human FIS1/Mitochondrial fission 1 protein/TTC11/CGI-135

50ug

2280

2052

现货

国产

CF28

Recombinant Human FIS1/Mitochondrial fission 1 protein/TTC11/CGI-135

500ug

12320

11088

现货

国产

CF28

Recombinant Human FIS1/Mitochondrial fission 1 protein/TTC11/CGI-135

1mg

17600

15840

现货

国产

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  • Catalog# CF28
    Source E.coli
    Description Recombinant Human Mitochondrial Fission 1 Protein/FIS1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Gly122) of Human FIS1 fused with a 6His tag at the C-terminus.
    Names Mitochondrial Fission 1 Protein, FIS1 Homolog, hFis1, Tetratricopeptide Repeat Protein 11, TPR Repeat Protein 11, FIS1, TTC11, CGI-135
    Accession # Q9Y3D6
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris, pH 8.0
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MEAVLNELVSVEDLLKFEKKFQSEKAAGSVSKSTQFEYAWCLVRSKYNDDIRKGIVLLEELLPKG SKEEQRDYVFYLAVGNYRLKEYEKALKYVRGLLQTEPQNNQAKELERLIDKAMKKDGVEHHHHHH
    Background Mitochondrial Fission 1 Protein (FIS1) is a member of the FIS1 family. FIS1 is a single-pass membrane protein and contains one TPR repeat. FIS1 is part of the mitochondrial complex that promotes mitochondrial fission. FIS1 can induce cytochrome C discharge from the mitochondrion to the cytosol, eventually leading to apoptosis. In addition, FIS1 participates in peroxisomal growth and division. The C-terminus of FIS1 is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.