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CG71
Recombinant Human FKBP4/Peptidyl-prolyl cis-trans isomerase FKBP4
10ug
360
324
现货
国产
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CG71
Recombinant Human FKBP4/Peptidyl-prolyl cis-trans isomerase FKBP4
50ug
840
756
现货
国产
-
CG71
Recombinant Human FKBP4/Peptidyl-prolyl cis-trans isomerase FKBP4
500ug
8960
8064
现货
国产
-
CG71
Recombinant Human FKBP4/Peptidyl-prolyl cis-trans isomerase FKBP4
1mg
12800
11520
现货
国产
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Catalog# CG71 Source E.coli Description Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP4/FKBP4 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ala459) of Human FKBP4 fused with a 6His tag at the C-terminus. Names Peptidyl-prolyl cis-trans isomerase FKBP4, 51kDa FK506-binding protein, 51kDa FK506-binding protein, 59kDa immunophilin, FK506-binding protein 4, FKBP59, HSP-binding immunophilin, immunophilin FKBP52, Rotamase, FKBP4 Accession # Q02790 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris,10%glycerol, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGT KFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVF EVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEG ENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWE MNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNL AMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAK TQLAVCQQRIRRQLAREKKLYANMFERLAEEENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQV ETEALEHHHHHH*Background FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.