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C461

Recombinant Human CX3CL1/Fractalkine

10ug

936

842.4

现货

国产

C461

Recombinant Human CX3CL1/Fractalkine

50ug

2800

2520

现货

国产

C461

Recombinant Human CX3CL1/Fractalkine

500ug

12320

11088

现货

国产

C461

Recombinant Human CX3CL1/Fractalkine

1mg

17600

15840

现货

国产

C461

Recombinant Human Fractalkine/CX3CL1

10ug

936

842.4

现货

国产

C461

Recombinant Human Fractalkine/CX3CL1

50ug

2800

2520

现货

国产

C461

Recombinant Human Fractalkine/CX3CL1

500ug

12320

11088

现货

国产

C461

Recombinant Human Fractalkine/CX3CL1

1mg

17600

15840

现货

国产

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  • Catalog# C461
    Source HEK293
    Description Recombinant Human Fractalkine is produced by transfected human cells. It is a secreted protein with sequence (Gln25-Arg339) of Human FKN fused with a polyhistidine tag at the C-terminus.
    Names Fractalkine, C-X3-C Motif Chemokine 1, CX3C Membrane-Anchored Chemokine, Neurotactin, Small-Inducible Cytokine D1, CX3CL1, FKN, NTT, SCYD1
    Accession # P78423
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    QHHGVTKCNITCSKMTSKIPVALLIHYQQNQASCGKRAIILETRQHRLFCADPKEQWVKDAMQHL DRQAAALTRNGGTFEKQIGEVKPRTTPAAGGMDESVVLEPEATGESSSLEPTPSSQEAQRALGTS PELPTGVTGSSGTRLPPTPKAQDGGPVGTELFRVPPVSTAATWQSSAPHQPGPSLWAEAKTSEAP STQDPSTQASTASSPAPEENAPSEGQRVWGQGQSPRPENSLEREEMGPVPAHTDAFQDWGPGSMA HVSVVPVSSEGTPSREPVASGSWTPKAEEPIHATMDPQRLGVLITPVPDAQAATRVDHHHHHH
    Background Human Fractalkine (CX3CL1) is a member of the CX3C family of chemokines. Human Fractalkine contains both chemokine and mucin domain. The soluble form of Fractalkine is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane bound form of Fractalkine promotes leukocytes adhesion to endothelial cells. Fractalkine regulates leukocyte adhesion and migration processes at the endothelium and binds to CX3CR1. Natural Human Fractalkine is produced as a long protein (373-amino acid). The mucin-like stalk permits it to bind to the cell surface.

     

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