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CI38
Recombinant Human CX3CL1/Fractalkine
10ug
1200
1080
现货
国产
-
CI38
Recombinant Human CX3CL1/Fractalkine
50ug
3520
3168
现货
国产
-
CI38
Recombinant Human CX3CL1/Fractalkine
500ug
12320
11088
现货
国产
-
CI38
Recombinant Human CX3CL1/Fractalkine
1mg
17600
15840
现货
国产
-
CI38
Recombinant Human Fractalkine/CX3CL1
10ug
1200
1080
现货
国产
-
CI38
Recombinant Human Fractalkine/CX3CL1
50ug
3520
3168
现货
国产
-
CI38
Recombinant Human Fractalkine/CX3CL1
500ug
12320
11088
现货
国产
-
CI38
Recombinant Human Fractalkine/CX3CL1
1mg
17600
15840
现货
国产
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Catalog# CI38 Source HEK293 Description Recombinant Mouse Fractalkine/C-X3-C motif chemokine 1/CX3C membrane-anchored chemokine/Neurotactin/Small-inducible cytokine D1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln25-Arg337) of Human CX3CL1 fused with a polyhistidine tag at the C-terminus. Names Fractalkine, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1, Cx3c, Fkn, Scyd1, CXC3, CXC3C, ABCD-3, SCYD1, C3Xkine, NTN, NTT Accession # O35188 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence QHLGMTKCEIMCDKMTSRIPVALLIRYQLNQESCGKRAIVLETTQHRRFCADPKEKWVQDAMKHL DHQAAALTKNGGKFEKRVDNVTPGITLATRGLSPSALTKPESATLEDLALELTTISQEARGTMGT SQEPPAAVTGSSLSTSEAQDAGLTAKPQSIGSFEAADISTTVWPSPAVYQSGSSSWAEEKATESP STTAPSPQVSTTSPSTPEENVGSEGQPPWVQGQDLSPEKSLGSEEINPVHTDNFQERGPGNTVHP SVAPISSEETPSPELVASGSQAPKIEEPIHATADPQKLSVLITPVPDTQAATRVDHHHHHH*Background Fractalkine(CX3CL1) is a single-pass type I membrane protein and belongs to the intercrine delta family. It consists of an extracellular NH2-terminal domain, a mucin-like stalk, a transmembrane α helix, and a short cytoplasmic tail. CX3CL1 exists in two forms: as a membrane-anchored or as a shed 80-95K glycoprotein. Soluble CX3CL1 is generated by limited proteolysis on the cell surface, and a disintegrin and metallopeptidase 10 (ADAM10) and ADAM17/tumor necrosis factor-α-converting enzyme (ADAM17/TACE) participate in this shedding. It has been suggested that ADAM10 acts in the constitutive shedding, and ADAM17 acts in response to cell activation. The protein may play a role in regulating leukocyte adhesion and migration processes at the endothelium.