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CD77
Recombinant Human Fructose-1,6-bisphosphatase 1/FBP1
10ug
640
576
现货
国产
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CD77
Recombinant Human Fructose-1,6-bisphosphatase 1/FBP1
50ug
1760
1584
现货
国产
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CD77
Recombinant Human Fructose-1,6-bisphosphatase 1/FBP1
500ug
12320
11088
现货
国产
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CD77
Recombinant Human Fructose-1,6-bisphosphatase 1/FBP1
1mg
17600
15840
现货
国产
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Catalog# CD77 Source Human Cells Description Recombinant Human Fructose-1,6-Bisphosphatase 1/FBPase 1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala2-Gln338) of Human FBPase 1 fused with a polyhistidine tag at the C-terminus. Names Fructose-1,6-bisphosphatase 1 ，FBPase 1 ，D-fructose-1,6-bisphosphate 1-phosphohydrolase 1 ，FBP Accession # P09467 Formulation Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 1mM DTT,10% glycerol, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence ADQAPFDTDVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTNV TGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLV SVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFIL VDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGG IFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVL EFLKVYEKHSAQVDHHHHHH*Background Fructose-1,6-bisphosphatase 1(FBP1) is a homotetramer protein and belongs to the FBPase class 1 family. It involves in carbohydrate biosynthesis; gluconeogenesis pathway. FBP1 is a gluconeogenesis regulatory protein which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBP1 deficiency is associated with hypoglycemia and metabolic acidosis. FBP1 regulates mouse endogenous glucose production. FBP1 coupled with phosphofructokinase (PFK) takes part in the metabolism of pancreatic islet cells.