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CE65
Recombinant Human GADD45A/DNA damage-inducible transcript 1 protein/DDDIT-1
10ug
1200
1080
现货
国产
-
CE65
Recombinant Human GADD45A/DNA damage-inducible transcript 1 protein/DDDIT-1
50ug
3520
3168
现货
国产
-
CE65
Recombinant Human GADD45A/DNA damage-inducible transcript 1 protein/DDDIT-1
500ug
12320
11088
现货
国产
-
CE65
Recombinant Human GADD45A/DNA damage-inducible transcript 1 protein/DDDIT-1
1mg
17600
15840
现货
国产
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Catalog# CE65 Source E.coli Description Recombinant Human Growth Arrest and DNA Damage-Inducible Protein GADD45 α/GADD45A is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Arg165) of Human GADD45A fused with a 6His tag at the N-terminus. Names Growth Arrest and DNA Damage-Inducible Protein GADD45 Alpha, DNA Damage-Inducible Transcript 1 Protein, DDIT-1, GADD45A, DDIT1, GADD45 Accession # P24522 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMTLEEFSAGEQKTERMDKVGDALEEVLSKALSQRTITVGVYEAAK LLNVDPDNVVLCLLAADEDDDRDVALQIHFTLIQAFCCENDINILRVSNPGRLAELLLLETDAGP AASEGAEQPPDLHCVLVTNPHSSQWKDPALSQLICFCRESRYMDQWVPVINLPERBackground Growth Arrest and DNA Damage-Inducible Protein GADD45 α (GADD45A) is a member of the GADD45 family. GADD45A can be induced by UV irradiation, X-rays, growth arrest and alkylating agents, of which can be mediated by some kinases other than PKC. GADD45A can interact with MAPK14, GADD45GIP1, PCNA. In T-cells, GADD45A functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. GADD45A may affect PCNA interaction with some cell division protein kinase complexes, stimulating DNA excision repair in vitro and inhibits entry of cells into S phase.