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C227

Recombinant Human Glial fibrillary acidic protein/GFAP

10ug

1200

1080

现货

国产

C227

Recombinant Human Glial fibrillary acidic protein/GFAP

50ug

3520

3168

现货

国产

C227

Recombinant Human Glial fibrillary acidic protein/GFAP

500ug

12320

11088

现货

国产

C227

Recombinant Human Glial fibrillary acidic protein/GFAP

1mg

17600

15840

现货

国产

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  • Catalog# C227
    Source E.coli
    Description Recombinant Human Glial Fibrillary Acidic Protein/GFAP is produced by our E. coli expression system. The target protein is expressed with sequence (Leu292-Met432) of Human GFAP fused with a His tag at the N-terminus.
    Names Glial Fibrillary Acidic Protein, GFAP
    Accession # P14136
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.25
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    MGSSHHHHHHSSGLVPRGSHMLTCDLESLRGTNESLERQMREQEERHVREAASYQEALARLEEEG QSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVS EGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
    Background Glial Fibrillary Acidic Protein (GFAP) is an intermediate filament (IF) protein which belongs to the intermediate filament family. GFAP is expressed in numerous cell types of the central nervous system (CNS), ependymal cells and phosphorylated by PKN1. GFAP, a class-III intermediate filament, is a cell-specific marker during the development of the central nervous system and distinguishes astrocytes from other glial cells. It is closely related to its non-epithelial family members, vimentin, desmin, and peripherin, which are all involved in the structure and function of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength, as well as the shape of cells but its exact function remains poorly understood.