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C664

Recombinant Human Glucagon/GCG

10ug

1200

1080

现货

国产

C664

Recombinant Human Glucagon/GCG

50ug

3520

3168

现货

国产

C664

Recombinant Human Glucagon/GCG

500ug

12320

11088

现货

国产

C664

Recombinant Human Glucagon/GCG

1mg

17600

15840

现货

国产

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  • Catalog# C664
    Source HEK293
    Description Recombinant Human Glucagon/GCG is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Lys180) of Human Glucagon fused with a polyhistidine tag at the C-terminus.
    Names Glucagon, Glicentin, Glicentin-Related Polypeptide, GRPP, Oxyntomodulin, OXM, OXY, Glucagon, Glucagon-Like Peptide 1, GLP-1, Incretin Hormone, Glucagon-like Peptide 1, GLP-1, Glucagon-Like Peptide 2, GLP-2, GCG
    Accession # P01275
    Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl,50%glycerol,1mM DTT, 0.2M NaCl,pH 8.0
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    RSLQDTEEKSRSFSASQADPLSDPDQMNEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNR NNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRGRRDFPEEVAIVEELGRRHADGS FSDEMNTILDNLAARDFINWLIQTKITDRK
    Background Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon can regulates blood glucose by decreasing glycolysis and increasing gluconeogenesis. In addition, Glucagon is involved in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon release is stimulated by hypoglycemia and inhibited by hyperglycemia, insulin, and somatostatin. In the glucagon antagonist, His-53 and Phe-58 are missing. This antagonist has been successfully utilized to reduce glucose concentration in vivo.