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CH13

Recombinant Human Hepcidin/HAMP/HEPC/LEAP1

10ug

1200

1080

现货

国产

CH13

Recombinant Human Hepcidin/HAMP/HEPC/LEAP1

50ug

3520

3168

现货

国产

CH13

Recombinant Human Hepcidin/HAMP/HEPC/LEAP1

500ug

13440

12096

现货

国产

CH13

Recombinant Human Hepcidin/HAMP/HEPC/LEAP1

1mg

19200

17280

现货

国产

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  • Catalog# CH13
    Source E.coli
    Description Recombinant Human Hepcidin/HAMP is produced with our E. coli expression system. The target protein is expressed with sequence (Asp60-Thr84) of Human HAMP fused with a GST tag at the N-terminus.
    Names Liver-expressed antimicrobial peptide 1, Putative liver tumor regressor, HEPC, LEAP1
    Accession # P81172
    Formulation Supplied as a 0.2 μm filtered solution of PBS, pH 7.4, 50% glycerol
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKL TQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEML KMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKS SKYIAWPLQGWQATFGGGDHPPKSDLVPRGSENLYFQGHMDTHFPICIFCCGCCHRSKCGMCCKT
    Background Hepcidin(HAMP)is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structures.