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C987
Recombinant Human HMGB2/High mobility group protein B2
10ug
1200
1080
现货
国产
-
C987
Recombinant Human HMGB2/High mobility group protein B2
50ug
3520
3168
现货
国产
-
C987
Recombinant Human HMGB2/High mobility group protein B2
500ug
12320
11088
现货
国产
-
C987
Recombinant Human HMGB2/High mobility group protein B2
1mg
17600
15840
现货
国产
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Catalog# C987 Source HEK293 Description Recombinant Human High Mobility Group Protein B2/HMGB2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gly2-Glu209) of Human HMGB2 fused with a 6His tag at the C-terminus. Names High Mobility Group Protein B2, High Mobility Group Protein 2, HMG-2, HMGB2, HMG2 Accession # P26583 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MGKGDPNKPRGKMSSYAFFVQTCREEHKKKHPDSSVNFAEFSKKCSERWKTMSAKEKSKFEDMAK SDKARYDREMKNYVPPKGDKKGKKKDPNAPKRPPSAFFLFCSEHRPKIKSEHPGLSIGDTAKKLG EMWSEQSAKDKQPYEQKAAKLKEKYEKDIAAYRAKGKSEAGKKGPGRPTGSKKKNEPEDEEEEEE EEDEDEEEEDEDEEVDHHHHHHBackground High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility group protein family. Members of this family are chromatin-associated and widely spread in the nucleus of higher eukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and has the ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bend DNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.