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C146
Recombinant Human HO-1/HMOX1/HSP32
10ug
840
756
现货
国产
-
C146
Recombinant Human HO-1/HMOX1/HSP32
50ug
2520
2268
现货
国产
-
C146
Recombinant Human HO-1/HMOX1/HSP32
500ug
12320
11088
现货
国产
-
C146
Recombinant Human HO-1/HMOX1/HSP32
1mg
17600
15840
现货
国产
-
C146
Recombinant Human HSP32/HO-1/HMOX1
10ug
840
756
现货
国产
-
C146
Recombinant Human HSP32/HO-1/HMOX1
50ug
2520
2268
现货
国产
-
C146
Recombinant Human HSP32/HO-1/HMOX1
500ug
12320
11088
现货
国产
-
C146
Recombinant Human HSP32/HO-1/HMOX1
1mg
17600
15840
现货
国产
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Catalog# C146 Source E.coli Description Recombinant Human Heme Oxygenase 1/HO-1 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Thr261) of Human HO-1. Names Heme Oxygenase 1, HO-1, HMOX1, HO, HO1 Accession # P09601 Formulation Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.4 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEI ERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLV AHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEMTPAV RQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRASNKVQDSAPVETPRGKPPLN TBackground Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HO-1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals, bromobenzene, endotoxin, oxidizing agents and UVA. HO-1 is involved in the regulation of cardiovascular function and response to a variety of stressors. Defects in HO-1 are the cause of Heme Oxygenase 1 deficiency, resulting in marked erythrocyte fragmentation and intravascular hemolysis, coagulation abnormalities, endothelial damage, and iron deposition in renal and hepatic tissues.