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CI68
Recombinant Human Hyaluronan-binding protein 2/HABP2
10ug
1200
1080
现货
国产
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CI68
Recombinant Human Hyaluronan-binding protein 2/HABP2
50ug
3520
3168
现货
国产
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CI68
Recombinant Human Hyaluronan-binding protein 2/HABP2
500ug
12320
11088
现货
国产
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CI68
Recombinant Human Hyaluronan-binding protein 2/HABP2
1mg
17600
15840
现货
国产
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Catalog# CI68 Source Human cells Description Recombinant Human HABP2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Gln279) of Human HABP2 fused with a polyhistidine tag at the C-terminus. Names Hyaluronan-binding protein 2, Factor VII-activating protease, Factor seven-activating protease, Hepatocyte growth factor activator-like protein, Plasma hyaluronan-binding protein Accession # Q14520 Formulation Lyophilized from PBS buffer with 2% sucrose Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 11X PBS.
Please aliquot the reconstituted solutionStorage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 4 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MTSTLPFSPQVSTPRSKFKRISSVLSIEFAATMFARMSDLHVLLLMALVGKTACGFSLMSLLESL DPDWTPDQYDYSYEDYNQEENTSSTLTHAENPDWYYTEDQADPCQPNPCEHGGDCLVHGSTFTCS CLAPFSGNKCQKVQNTCKDNPCGRGQCLITQSPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGA TCSRHKRRSKFTCACPDQFKGKFCEIGSDDCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENY NMFMEDAETHGIGEHNFCRNPDADEKPWCFIKVTNDKVKWEYCDVSACSAQAVDHHHHHHBackground Hyaluronan-binding protein 2（HABP2） is an extracellular serine protease which binds hyaluronic acid. It secreted as an inactive single-chain precursor and is then activated to a heterodimeric form, which consists of a 50 kDa heavy and a 27 kDa light chain linked by a disulfide bond. HABP2 is involved in cell adhesion, it can cleave the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' , but not the gamma-chain of fibrinogen. As a result of this, it does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator to the active two chain form, activates coagulation factor VII.