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C475

Recombinant Human B7-H2/B7 Homolog 2

10ug

840

756

现货

国产

C475

Recombinant Human B7-H2/B7 Homolog 2

50ug

2520

2268

现货

国产

C475

Recombinant Human B7-H2/B7 Homolog 2

500ug

12320

11088

现货

国产

C475

Recombinant Human B7-H2/B7 Homolog 2

1mg

17600

15840

现货

国产

C475

Recombinant Human ICOS Ligand/ICOSLG

10ug

840

756

现货

国产

C475

Recombinant Human ICOS Ligand/ICOSLG

50ug

2520

2268

现货

国产

C475

Recombinant Human ICOS Ligand/ICOSLG

500ug

12320

11088

现货

国产

C475

Recombinant Human ICOS Ligand/ICOSLG

1mg

17600

15840

现货

国产

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  • Catalog# C475
    Source HEK293
    Description Recombinant Human Inducible Co-Stimulator Ligand/ICOSLG produced by transfected human cells is a secreted protein with sequence (Asp19-Ser258) of Human ICOSLG fused with a polyhistidine tag at the C-terminus.
    Names ICOS Ligand, B7 Homolog 2, B7-H2, B7-Like Protein Gl50, B7-Related Protein 1, B7RP-1, CD275, ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
    Accession # O75144
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    DTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESKTVVTYHIPQNSSLENVDSRYRNR ALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHS PSQDELTFTCTSINGYPRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNI GCCIENVLLQQNLTVGSQTGNDIGERDKITENPVSTGEKNAATWSVDHHHHHH
    Background Inducible Co-Stimulator Ligand (ICOSLG) belongs to the immunoglobulin superfamily. ICOSLG contains Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. ICOSLG acts as a costimulatory signal for T-cell proliferation and cytokine secretion, it also induces B-cell proliferation and differentiation into plasma cells. It could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. ICOSLG is widely expressed lymph nodes, leukocytes and spleen, detected on activated monocytes and dendritic cells.