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CC08

Recombinant Human IL-10RB/Interleukin-10 receptor subunit beta

10ug

400

360

现货

国产

CC08

Recombinant Human IL-10RB/Interleukin-10 receptor subunit beta

50ug

1200

1080

现货

国产

CC08

Recombinant Human IL-10RB/Interleukin-10 receptor subunit beta

500ug

5200

4680

现货

国产

CC08

Recombinant Human IL-10RB/Interleukin-10 receptor subunit beta

1mg

6800

6120

现货

国产

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  • Catalog# CC08
    Source HEK293
    Description Recombinant Human Interleukin-10 receptor subunit beta/ IL-10RB is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met20-Ser220) of Human IL10RB fused with a polyhistidine tag at the C-terminus.
    Names Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family.
    Accession # Q08334
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYRIFQDKCMNTTLTECDFSSLSKYGD HTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNVY NSWTYNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTH DETVPSVDHHHHHH
    Background IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.

     

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