产品中心
-
产品货号
产品名称
规格
销售价
会员价
货期
产地
订购
-
CC08
Recombinant Human IL-10RB/Interleukin-10 receptor subunit beta
10ug
400
360
现货
国产
-
CC08
Recombinant Human IL-10RB/Interleukin-10 receptor subunit beta
50ug
1200
1080
现货
国产
-
CC08
Recombinant Human IL-10RB/Interleukin-10 receptor subunit beta
500ug
5200
4680
现货
国产
-
CC08
Recombinant Human IL-10RB/Interleukin-10 receptor subunit beta
1mg
6800
6120
现货
国产
- 产品简介
- 使用说明
- 相关产品
- 参考文献
- 购买咨询
Catalog# CC08 Source HEK293 Description Recombinant Human Interleukin-10 receptor subunit beta/ IL-10RB is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met20-Ser220) of Human IL10RB fused with a polyhistidine tag at the C-terminus. Names Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family. Accession # Q08334 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MVPPPENVRMNSVNFKNILQWESPAFAKGNLTFTAQYLSYRIFQDKCMNTTLTECDFSSLSKYGD HTLRVRAEFADEHSDWVNITFCPVDDTIIGPPGMQVEVLADSLHMRFLAPKIENEYETWTMKNVY NSWTYNVQYWKNGTDEKFQITPQYDFEVLRNLEPWTTYCVQVRGFLPDRNKAGEWSEPVCEQTTH DETVPSVDHHHHHHBackground IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.
