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C615
Recombinant Human IL-27 R alpha/WSX-1/TCCR
10ug
640
576
现货
国产
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C615
Recombinant Human IL-27 R alpha/WSX-1/TCCR
50ug
1760
1584
现货
国产
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C615
Recombinant Human IL-27 R alpha/WSX-1/TCCR
500ug
12320
11088
现货
国产
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C615
Recombinant Human IL-27 R alpha/WSX-1/TCCR
1mg
17600
15840
现货
国产
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Catalog# C615 Source HEK293 Description Recombinant Human Interleukin-27 Receptor Subunit α/IL-27Rα is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gln33-Lys516) of Human IL27RA fused with a polyhistidine tag at the C-terminus. Names Interleukin-27 Receptor Subunit Alpha, IL-27 Receptor Subunit Alpha, IL-27R Subunit Alpha, IL-27R-Alpha, IL-27RA, Cytokine Receptor-Like 1, Type I T-Cell Cytokine Receptor, TCCR, WSX-1, ZcytoR1, IL27RA, CRL1, TCCR, WSX1 Accession # Q6UWB1 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence QGSAGPLQCYGVGPLGDLNCSWEPLGDLGAPSELHLQSQKYRSNKTQTVAVAAGRSWVAIPREQL TMSDKLLVWGTKAGQPLWPPVFVNLETQMKPNAPRLGPDVDFSEDDPLEATVHWAPPTWPSHKVL ICQFHYRRCQEAAWTLLEPELKTIPLTPVEIQDLELATGYKVYGRCRMEKEEDLWGEWSPILSFQ TPPSAPKDVWVSGNLCGTPGGEEPLLLWKAPGPCVQVSYKVWFWVGGRELSPEGITCCCSLIPSG AEWARVSAVNATSWEPLTNLSLVCLDSASAPRSVAVSSIAGSTELLVTWQPGPGEPLEHVVDWAR DGDPLEKLNWVRLPPGNLSALLPGNFTVGVPYRITVTAVSASGLASASSVWGFREELAPLVGPTL WRLQDAPPGTPAIAWGEVPRHQLRGHLTHYTLCAQSGTSPSVCMNVSGNTQSVTLPDLPWGPCEL WVTASTIAGQGPPGPILRLHLPDNTLRWKVDHHHHHHBackground Interleukin-27 Receptor Subunit α (IL-27Rα) is a single-pass type I membrane protein that belongs to the type I cytokine receptor family of Type 2 subfamily. It contains 3 Fibronectin type-III domains. The IL27RA gene encodes a 484 amino acid extracellular region, a 21 amino acid transmembrane segment, and a 99 amino acid cytoplasmic domain. IL-27Rα is highly expressed in lymphoid tissues such as spleen, lymph nodes, and peripheral blood leukocytes. IL-27Rα eequires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. IL-27Rα is also involved in the regulation of Th1-type immune responses. It also appears to be involved in innate defense mechanisms.