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CG79
Recombinant Human Inosine-5'-monophosphate dehydrogenase 2/IMPDH2
10ug
840
756
现货
国产
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CG79
Recombinant Human Inosine-5'-monophosphate dehydrogenase 2/IMPDH2
50ug
2520
2268
现货
国产
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CG79
Recombinant Human Inosine-5'-monophosphate dehydrogenase 2/IMPDH2
500ug
12320
11088
现货
国产
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CG79
Recombinant Human Inosine-5'-monophosphate dehydrogenase 2/IMPDH2
1mg
17600
15840
现货
国产
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Catalog# CG79 Source E.coli Description Recombinant Human Inosine-5'-monophosphate dehydrogenase 2/IMPDH2 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Phe514) of Human IMPDH2 fused with a 6His tag at the N-terminus. Names Inosine-5'-monophosphate dehydrogenase 2, IMPDH2, IMP dehydrogenase 2, IMPD 2, IMPDH 2, IMPDH-II, IMPD2. Accession # P12268 Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFT ADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKY EQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFL EEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVV TAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNV GHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEAD KIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVE GGVHSLHSYEKRLFBackground IMPDH2 is a cytosolic enzyme which belongs to the IMPDH/GMPR family. IMPDH2 catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'- monophosphate. IMPDH2 is consequently involved in maintaining cellular guanine deoxy- and ribonucleotide pools required for DNA and RNA synthesis. In addition, IMPDH1 and IMPDH2 are targets for the important immunosuppressive drug, mycophenolic acid (MPA).