产品中心

产品货号

产品名称

规格

销售价

会员价

货期

产地

订购

CI70

Recombinant Human Interferon gamma receptor 1/IFNGR1

10ug

400

360

现货

国产

CI70

Recombinant Human Interferon gamma receptor 1/IFNGR1

50ug

1200

1080

现货

国产

CI70

Recombinant Human Interferon gamma receptor 1/IFNGR1

500ug

9840

8856

现货

国产

CI70

Recombinant Human Interferon gamma receptor 1/IFNGR1

1mg

14080

12672

现货

国产

  • 产品简介
  • 使用说明
  • 相关产品
  • 参考文献
  • 购买咨询
  • Catalog# CI70
    Source Human cells
    Description Recombinant Human IFNGR1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu18-Ser245) of Human IFNGR1 fused with a polyhistidine tag at the C-terminus.
    Names Interferon gamma receptor 1,IFNGR1,CDw119,CD119
    Accession # P15260
    Formulation Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH 7.4
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 99% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    EMGTADLGPSSVPTPTNVTIESYNMNPIVYWEYQIMPQVPVFTVEVKNYGVKNSEWIDACINISH HYCNISDHVGDPSNSLWVRVKARVGQKESAYAKSEEFAVCRDGKIGPPKLDIRKEEKQIMIDIFH PSVFVNGDEQEVDYDPETTCYIRVYNVYVRMNGSEIQYKILTQKEDDCDEIQCQLAIPVSSLNSQ YCVSAEGVLHVWGVTTEKSKEVCITIFNSSIKGVDHHHHHH
    Background Interferon gamma receptor 1(IFNGR1) encoded by the IFNGR1 gene, is a single-pass type 1 membrane protein which belongs to the type II cytokine receptor family. IFNGR1 is phosphorylated at Ser/Thr residues after translation. IFNGR1 is a receptor for interferon gamma, two receptors bind one interferon gama dimer. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.