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CF18
Recombinant Human Interferon regulatory factor 5/IRF5
10ug
1200
1080
现货
国产
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CF18
Recombinant Human Interferon regulatory factor 5/IRF5
50ug
3520
3168
现货
国产
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CF18
Recombinant Human Interferon regulatory factor 5/IRF5
500ug
13440
12096
现货
国产
-
CF18
Recombinant Human Interferon regulatory factor 5/IRF5
1mg
19200
17280
现货
国产
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Catalog# CF18 Source E.coli Description Recombinant Human Interferon Regulatory Factor 5/IRF5 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Gln498) of Human IRF5 fused with a 6His tag at the C-terminus. Names Interferon Regulatory Factor 5, IRF-5, IRF5 Accession # Q13568 Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRHGPSQDGDNTIFK AWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFRLIYDGPRDMPPQPYKIYEVCSNGPAPTDS QPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPPTLRPPTLQPPTLQPPVVLGPPAP DPSPLAPPPGNPAGFRELLSEVLEPGPLPASLPPAGEQLLPDLLISPHMLPLTDLEIKFQYRGRP PRALTISNPHGCRLFYSQLEATQEQVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGL ILQLQGQDLYAIRLCQCKVFWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTP PPFEIFFCFGEEWPDRKPREKKLITVQVVPVAARLLLEMFSGELSWSADSIRLQISNPDLKDRMV EQFKELHHIWQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQLEHHHHHHBackground Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis.