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CE49

Recombinant Human Isopentenyl pyrophosphate isomerase 2/IDI2

10ug

1200

1080

现货

国产

CE49

Recombinant Human Isopentenyl pyrophosphate isomerase 2/IDI2

50ug

3520

3168

现货

国产

CE49

Recombinant Human Isopentenyl pyrophosphate isomerase 2/IDI2

500ug

12320

11088

现货

国产

CE49

Recombinant Human Isopentenyl pyrophosphate isomerase 2/IDI2

1mg

17600

15840

现货

国产

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  • Catalog# CE49
    Source E.coli
    Description Recombinant Human Isopentenyl Pyrophosphate Isomerase 2/IPP Isomerase 2 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Val227) of Human IDI2 fused with a 6His tag at the N-terminus.
    Names Isopentenyl-Diphosphate Delta-Isomerase 2, Isopentenyl Pyrophosphate Isomerase 2, IPP Isomerase 2, IPPI2, IDI2
    Accession # Q9BXS1
    Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 0.1mM PMSF, pH 8.0
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    MGSSHHHHHHSSGLVPRGSHMSDINLDWVDRRQLQRLEEMLIVVDENDKVIGADTKRNCHLNENI EKGLLHRAFSVVLFNTKNRILIQQRSDTKVTFPGYFTDSCSSHPLYNPAELEEKDAIGVRRAAQR RLQAELGIPGEQISPEDIVFMTIYHHKAKSDRIWGEHEICYLLLVRKNVTLNPDPSETKSILYLS QEELWELLEREARGEVKVTPWLRTIAERFLYRWWPHLDDVTPFVELHKIHRV
    Background Isopentenyl Pyrophosphate Isomerase 2 (IDI2) belongs to the IPP isomerase type 1 family. Both isozymes, IDI1 and IDI2 are localized to the peroxisome by a PTS1-dependent pathway. IDI2 is expressed in skeletal muscle, which contains one nudix hydrolase domain. IDI2 binds one magnesium per subunit. IDI2 catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). It is reported that IDI2 is regulated independently from IDI1, by a mechanism that may involve PPAR-α.