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C119
Recombinant Human CXCL11/I-TAC
10ug
936
842.4
现货
国产
-
C119
Recombinant Human CXCL11/I-TAC
50ug
2800
2520
现货
国产
-
C119
Recombinant Human CXCL11/I-TAC
500ug
12320
11088
现货
国产
-
C119
Recombinant Human CXCL11/I-TAC
1mg
17600
15840
现货
国产
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C119
Recombinant Human I-TAC/CXCL11
10ug
936
842.4
现货
国产
-
C119
Recombinant Human I-TAC/CXCL11
50ug
2800
2520
现货
国产
-
C119
Recombinant Human I-TAC/CXCL11
500ug
12320
11088
现货
国产
-
C119
Recombinant Human I-TAC/CXCL11
1mg
17600
15840
现货
国产
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Catalog# C119 Source E.coli Description Recombinant Human C-X-C Motif Chemokine 11/CXCL11 is produced with our E. coli expression system. The target protein is expressed with sequence (Phe22-Phe94) of Human CXCL11. Names C-X-C Motif Chemokine 11, Beta-R1, H174, Interferon Gamma-Inducible Protein 9, IP-9, Interferon-Inducible T-Cell Alpha Chemoattractant, I-TAC, Small-Inducible Cytokine B11, CXCL11, ITAC, SCYB11, SCYB9B Accession # O14625 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 2.5mM EDTA, 500mM NaCl, pH 9.0 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence MFPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKIEVIITLKENKGQRCLNPKSKQARLI IKKVERKNFBackground Chemokine Ligand 11 (CXCL11) is a non-ELR (lacking the Glu-Leu-Arg tripeptide motif) CXC chemokine. CXCL11 is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. Gene expression of CXCL11 is strongly induced by IFN-γ and IFN-β, and weakly induced by IFN-α. This chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. CXCL11 is chemotactic for activated T cells. Its gene is located on human chromosome 4 along with many other members of the CXC chemokine family. CXCL11 cDNA encodes a 94 amino acid residue precursor protein with a 21 amino acid residue putative signal sequence, which is cleaved to form the mature 73 amino acid residue protein. CXCL11 shares 36% and 37% amino acid sequence homology with IP-10 and MIG (two other known human non-ELR CXC chemokines), respectively. Mouse CXCL11 exhibits 68% sequence homology with humanCXCL11. In humans, CXCL11, IP-10 and MIG all map to the same locus on chromosome 4.