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CI25
Recombinant Human ITIH3/Inter-alpha-trypsin inhibitor heavy chain H3 Protein
10ug
640
576
现货
国产
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CI25
Recombinant Human ITIH3/Inter-alpha-trypsin inhibitor heavy chain H3 Protein
50ug
2000
1800
现货
国产
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CI25
Recombinant Human ITIH3/Inter-alpha-trypsin inhibitor heavy chain H3 Protein
500ug
12320
11088
现货
国产
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CI25
Recombinant Human ITIH3/Inter-alpha-trypsin inhibitor heavy chain H3 Protein
1mg
17600
15840
现货
国产
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Catalog# CI25 Source HEK293 Description Recombinant Human Inter-alpha-trypsin inhibitor heavy chain H3/ITIH3 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Leu35-Asp651) of Human ITIH3 fused with a polyhistidine tag at_x0000_the C-termin Names Inter-alpha-trypsin inhibitor heavy chain H3,ITI heavy chain H3,ITI-HC3,Inter-alpha-inhibitor heavy chain 3,Serum-derived hyaluronan-associated protein,SHAP Accession # Q06033 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl, pH7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence LPEGVANGIEVYSTKINSKVTSRFAHNVVTMRAVNRADTAKEVSFDVELPKTAFITNFTLTIDGV TYPGNVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHK GKYEMYLKVQPKQLVKHFEIEVDIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPS LDQQRSCPTCTDSLLNGDFTITYDVNRESPGNVQIVNGYFVHFFAPQGLPVVPKNVAFVIDISGS MAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKEHLVQATPENLQEARTFVKSMEDKGM TNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYN LGFGNNLNYNFLENMALENHGFARRIYEDSDADLQLQGFYEEVANPLLTGVEMEYPENAILDLTQ NTYQHFYDGSEIVVAGRLVDEDMNSFKADVKGHGATNDLTFTEEVDMKEMEKALQERDYIFGNYI ERLWAYLTIEQLLEKRKNAHGEEKENLTARALDLSLKYHFVTPLTSMVVTKPEDNEDERAIADKP GEDAEATPVSPAMSYLTSYQPPQNPYYYVDGDVDHHHHHH*Background ITIH3, which is short for Inter-alpha-trypsin inhibitor heavy chain H3, is a 890 aa. protein. It is secreted expression, and belongs to the ITIH family. I-alpha-I plasma protease inhibitors are assembled from one or two heavy chains (H1, H2 or H3) and one light chain, bikunin. Inter-alpha-inhibitor (I-alpha-I) is composed of H1, H2 and bikunin, inter-alpha-like inhibitor (I-alpha-LI) of H2 and bikunin, and pre-alpha-inhibitor (P-alpha-I) of H3 and bikunin. ITTH3 may act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.