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C310
Recombinant Human CD158d/KIR2DL4
10ug
640
576
现货
国产
-
C310
Recombinant Human CD158d/KIR2DL4
50ug
1760
1584
现货
国产
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C310
Recombinant Human CD158d/KIR2DL4
500ug
12320
11088
现货
国产
-
C310
Recombinant Human CD158d/KIR2DL4
1mg
17600
15840
现货
国产
-
C310
Recombinant Human KIR2DL4/CD158d
10ug
640
576
现货
国产
-
C310
Recombinant Human KIR2DL4/CD158d
50ug
1760
1584
现货
国产
-
C310
Recombinant Human KIR2DL4/CD158d
500ug
12320
11088
现货
国产
-
C310
Recombinant Human KIR2DL4/CD158d
1mg
17600
15840
现货
国产
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Catalog# C310 Source HEK293 Description Recombinant Human Killer Cell Immunoglobulin-Like Receptor 2DL4/KIR2DL4 produced by transfected human cells is a secreted protein with sequence (Trp22-His242) of Human KIR2DL4 fused with a polyhistidine tag at the C-terminus. Names Killer Cell Immunoglobulin-Like Receptor 2DL4, CD158 Antigen-Like Family Member D, G9P, Killer Cell Inhibitory Receptor 103AS, KIR-103AS, MHC Class I NK Cell Receptor KIR103AS, CD158d, KIR2DL4, CD158D, KIR103AS Accession # Q99706 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence WAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFTLYKKDGVPVPELYNRIFWNSFLISP VTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVTGLYEKPSLTARPGPTVRTGENVTLSCSSQSS FDIYHLSREGEAHELRLPAVPSINGTFQADFPLGPATHGETYRCFGSFHGSPYEWSDASDPLPVS VTGNPSSSWPSPTEPSFKTGIARHLHVDHHHHHHBackground Killer cell immunoglobulin-like receptor 2DL4(KIR2DL4) is a Single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.