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CA95

Recombinant Human LCAT/Lecithin-cholesterol acyltransferase

10ug

1200

1080

现货

国产

CA95

Recombinant Human LCAT/Lecithin-cholesterol acyltransferase

50ug

3520

3168

现货

国产

CA95

Recombinant Human LCAT/Lecithin-cholesterol acyltransferase

500ug

12320

11088

现货

国产

CA95

Recombinant Human LCAT/Lecithin-cholesterol acyltransferase

1mg

17600

15840

现货

国产

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  • Catalog# CA95
    Source Human Cells
    Description Recombinant Human Lecithin-cholesterol acyltransferase/LCAT is produced with our Mammalian expression system. The target protein is expressed with sequence (Phe25-Glu440) of Human LCAT fused with a 6His tag at the C-terminus.
    Names Phosphatidylcholine-sterol acyltransferase, also named Lecithin-cholesterol acyltransferase, Phospholipid-cholesterol acyltransferase and LACT, is an extracellular cholesterol esterifying enzyme which belongs to the AB hydrolase superfamily.
    Accession # P04180
    Formulation Lyophilized from a 0.2 μm filtered solution of 50mM Acetate Buffer pH-4.0.
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    Amino Acid Sequence
    FWLLNVLFPPHTTPKAELSNHTRPVILVPGCLGNQLEAKLDKPDVVNWMCYRKTEDFFTIWLDLN MFLPLGVDCWIDNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVN NGYVRDETVRAAPYDWRLEPGQQEEYYRKLAGLVEEMHAAYGKPVFLIGHSLGCLHLLYFLLRQP QAWKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPIMSSIKLKEEQRITTTSPWMFPSRMAWP EDHVFISTPSFNYTGRDFQRFFADLHFEEGWYMWLQSRDLLAGLPAPGVEVYCLYGVGLPTPRTY IYDHGFPYTDPVGVLYEDGDDTVATRSTELCGLWQGRQPQPVHLLPLHGIQHLNMVFSNLTLEHI NAILLGAYRQGPPASPTASPEPPPPEVDHHHHHH
    Background Lipase family. The gene encoding this protein is expressed mainly in brain, liver and testes,followed by secreting into plasma and cerebral spinal fluid. The esterification of cholesterol is required for cholesterol transport. LCAT is a central enzyme in the extracellular metabolism of plasma lipoproteins. Defects in LCAT are the cause of lecithin-cholesterol acyltransferase deficiency (LCATD) and a cause of fish-eye disease (FED).