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CE69
Recombinant Human MBIP/MAP3K12-binding inhibitory protein 1
10ug
1200
1080
现货
国产
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CE69
Recombinant Human MBIP/MAP3K12-binding inhibitory protein 1
50ug
3520
3168
现货
国产
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CE69
Recombinant Human MBIP/MAP3K12-binding inhibitory protein 1
500ug
12320
11088
现货
国产
-
CE69
Recombinant Human MBIP/MAP3K12-binding inhibitory protein 1
1mg
17600
15840
现货
国产
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Catalog# CE69 Source E.coli Description Recombinant Human MAP3K12-Binding Inhibitory Protein 1/MBIP is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Pro344) of Human MBIP fused with a His tag at the N-terminus. Names MAP3K12-Binding Inhibitory Protein 1, MAPK Upstream Kinase-Binding Inhibitory Protein, MUK-Binding Inhibitory Protein, MBIP Accession # Q9NS73 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris, pH8.0 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMAAATEHNRPSSGDRNLERRCSPNLSREVLYEIFRSLHTLVGQLD LRDDVVKITIDWNKLQSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMG NKNEVNDKFSIGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEIN ENNVREFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVYTYGPQTRPEGIPGSGHKPNSML RDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVSFSGKRRKV QPPQQNYSLAELDEKISALKQALLRKSREAESMATHHLPLEHHHHHHBackground MAP3K12-binding inhibitory protein 1 (MBIP) is a 39kD protein high expression in the heart and lung. It is a component of the ADA2A-containing complex (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4, and composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5. It’s function to inhibit the MAP3K12 activity to induce the activation of the JNK/SAPK pathway.