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产品货号
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会员价
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CG86
Recombinant Human Methylated-DNA--protein-cysteine methyltransferase /MGMT
10ug
760
684
现货
国产
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CG86
Recombinant Human Methylated-DNA--protein-cysteine methyltransferase /MGMT
50ug
2280
2052
现货
国产
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CG86
Recombinant Human Methylated-DNA--protein-cysteine methyltransferase /MGMT
500ug
12320
11088
现货
国产
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CG86
Recombinant Human Methylated-DNA--protein-cysteine methyltransferase/MGMT
1mg
17600
15840
现货
国产
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Catalog# CG86 Source E.coli Description Recombinant Human Methylated-DNA--protein-cysteine methyltransferase/MGMT is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asn207) of Human MGMT fused with a 6His tag at the N-terminus. Names ' Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNAmethyltransferase,O-6-methylguanine-DNA-alkyltransferase, MGMT' Accession # P16455 Formulation Supplied as a 0.2 μm filtered solution of 20mMTris-HCl,1mM EDTA, pH 8.0 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MGSSHHHHHHSSGLVPRGSHMDKDCEMKRTTLDSPLGKLELSGCEQGLHEIKLLGKGTSAADAVE VPAPAAVLGGPEPLMQCTAWLNAYFHQPEAIEEFPVPALHHPVFQQESFTRQVLWKLLKVVKFGE VISYQQLAALAGNPKAARAVGGAMRGNPVPILIPCHRVVCSSGAVGNYSGGLAVKEWLLAHEGHR LGKPGLGGSSGLAGAWLKGAGATSGSPPAGRNBackground 'MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular defense against the biological effects of O6-methylguanine in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. MGMT catalyzes the chemical reaction: DNA (containing 6-O-methylguanine) and proteinL-cysteine into DNA (without 6-O-methylguanine) and protein S-methyl-L-cysteine.'