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CH27

Recombinant Human MIF/Macrophage migration inhibitory factor

10ug

840

756

现货

国产

CH27

Recombinant Human MIF/Macrophage migration inhibitory factor

50ug

2520

2268

现货

国产

CH27

Recombinant Human MIF/Macrophage migration inhibitory factor

500ug

12320

11088

现货

国产

CH27

Recombinant Human MIF/Macrophage migration inhibitory factor

1mg

17600

15840

现货

国产

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  • Catalog# CH27
    Source E.coli
    Description Recombinant Mouse Macrophage migration inhibitory factor/MIF is produced with our E. coli expression system. The target protein is expressed with sequence (Pro2-Ala115) of Mouse MIF fused with a polyhistidine tag at the C-terminus.
    Names Macrophage migration inhibitory factor, Delayed early response protein 6, DER6, Glycosylation-inhibiting factor, GIF, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase,
    Accession # P34884
    Formulation Lyophilized from a 0.2 μm filtered solution of PBS
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    PMFIVNTNVPRASVPEGFLSELTQQLAQATGKPAQYIAVHVVPDQLMTFSGTNDPCALCSLHSIG KIGGAQNRNYSKLLCGLLSDRLHISPDRVYINYYDMNAANVGWNGSTFALEHHHHHH
    Background Macrophage migration inhibitory factor(MIF) is a secreted protein and belongs to the MIF family. MIF is an important regulator of innate immunity. The circulating MIF binds to CD74 on other immune cells to trigger an acute immune response. Hence MIF is classified as an inflammatory cytokine. Furthermore glucocorticoids also stimulate white blood cells to release MIF and hence MIF partially counter acts the inhibitory effects that glucocorticoids have on the immune system. Finally trauma activates the anterior pituitary gland to release MIF.