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CH33

Recombinant Human MIF/Macrophage migration inhibitory factor

10ug

1200

1080

现货

国产

CH33

Recombinant Human MIF/Macrophage migration inhibitory factor

50ug

3520

3168

现货

国产

CH33

Recombinant Human MIF/Macrophage migration inhibitory factor

500ug

13440

12096

现货

国产

CH33

Recombinant Human MIF/Macrophage migration inhibitory factor

1mg

19200

17280

现货

国产

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  • Catalog# CH33
    Source E.coli
    Description Recombinant Human Macrophage migration inhibitory factor/MIF is produced with our E. coli express system. The target protein is expressed with sequence Met1-Ala115 of Human MIF.
    Names Macrophage migration inhibitory factor, MIF, MMIF, Glycosylation-inhibiting factor, GLIF, L-dopachrome tautomerase, Phenylpyruvate tautomerase
    Accession # P14174
    Formulation Supplied as a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSI GKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
    Background 'Human MIF is a 12.5 kDa, 115 amino acid (aa) nonglycosylated polypeptide that is synthesized without a signal sequence .Secretion occurs nonclassically via an ABCA1 transporter.Pro-inflammatory cytokine.Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of acrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.'