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C297

Recombinant Human MOB kinase activator 1A/MOB1A/MOBKL1B

10ug

1200

1080

现货

国产

C297

Recombinant Human MOB kinase activator 1A/MOB1A/MOBKL1B

50ug

3520

3168

现货

国产

C297

Recombinant Human MOB kinase activator 1A/MOB1A/MOBKL1B

500ug

12320

11088

现货

国产

C297

Recombinant Human MOB kinase activator 1A/MOB1A/MOBKL1B

1mg

17600

15840

现货

国产

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  • Catalog# C297
    Source E.coli
    Description Recombinant Human MOB Kinase Activator 1A/MOB1A is produced by our E. coli expression system. The target protein is expressed with sequence (Ser2-Arg216) of Human MOB1A fused with a 6His tag at the C-terminus.
    Names MOB Kinase Activator 1A, Mob1 Alpha, Mob1A, Mob1 Homolog 1B, Mps One Binder Kinase Activator-like 1B, MOB1A, C2orf6, MOB4B, MOBK1B, MOBKL1B
    Accession # Q9H8S9
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 0.15M NaCl, pH 8.0
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRQAVMLPEGEDLNEWIAVNTVDFF NQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDET LFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNL IDRRELAPLQELIEKLGSKDRLEHHHHHH
    Background MOB Kinase Activator 1A (MOB1A) belongs to the MOB1/phocein family, which acts as an activator of LATS1/2 in the Hippo signaling pathway, plays a key role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. MOBKL1B stimulates the kinase activity of STK38 and STK38L. MOBKL1B binds to and regulate downstream targets such as the NDR-family protein kinases and LATS1 kinase.