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C802
Recombinant Human Myelin peripheral protein/MPZ
10ug
1200
1080
现货
国产
-
C802
Recombinant Human Myelin peripheral protein/MPZ
50ug
3520
3168
现货
国产
-
C802
Recombinant Human Myelin peripheral protein/MPZ
500ug
12320
11088
现货
国产
-
C802
Recombinant Human Myelin peripheral protein/MPZ
1mg
17600
15840
现货
国产
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Catalog# C802 Source HEK293 Description Recombinant Human Myelin Protein P0/MPZ is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ile30-Arg153) of Human MPZ fused with a 6His tag at the C-terminus. Names Myelin Protein P0, Myelin Peripheral Protein, MPP, Myelin Protein Zero, MPZ Accession # P25189 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence IVVYTDREVHGAVGSRVTLHCSFWSSEWVSDDISFTWRYQPEGGRDAISIFHYAKGQPYI DEVG TFKERIQWVGDPRWKDGSIVIHNLDYSDNGTFTCDVKNPPDIVGKTSQVTLYVFEK VPTRVDHH HHHHBackground Myelin Protein P0 (MPZ) is a single-pass type I membrane glycoprotein which belongs to the myelin P0 protein family. MPZ contains one Ig-like V-type (immunoglobulin-like) domain, absent in the central nervous system. MPZ is a major component of the myelin sheath in peripheral nerves. It is postulated that MPZ is a structural element in the formation and stabilisation of peripheral nerve myelin, holding its characteristic coil structure together by the interaction of its positively-charged domain with acidic lipids in the cytoplasmic face of the opposed bilayer, and by interaction between hydrophobic globular of adjacent extracellular domains. Defects in MPZ associated with Charcot-Marie-Tooth disease and Dejerine-Sottas disease.