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C056
Recombinant Human CXCL7/NAP-2
10ug
1200
1080
现货
国产
-
C056
Recombinant Human CXCL7/NAP-2
50ug
3520
3168
现货
国产
-
C056
Recombinant Human CXCL7/NAP-2
500ug
12320
11088
现货
国产
-
C056
Recombinant Human CXCL7/NAP-2
1mg
17600
15840
现货
国产
-
C056
Recombinant Human NAP-2/CXCL7
10ug
1200
1080
现货
国产
-
C056
Recombinant Human NAP-2/CXCL7
50ug
3520
3168
现货
国产
-
C056
Recombinant Human NAP-2/CXCL7
500ug
12320
11088
现货
国产
-
C056
Recombinant Human NAP-2/CXCL7
1mg
17600
15840
现货
国产
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Catalog# C056 Source E.coli Description Recombinant Human C-X-C Motif Chemokine Ligand 7/CXCL7 produced in E. coli is a single non-glycosylated polypeptide chain containing 70 amino acids with a molecular mass of 7.6 kD. Names Platelet Basic Protein, PBP, C-X-C Motif Chemokine 7, Leukocyte-Derived Growth Factor, LDGF, Macrophage-Derived Growth Factor, MDGF Small-Inducible Cytokine B7, PPBP, CTAP3, CXCL7, SCYB7, TGB1, THBGB1 Accession # P02775 Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Biological Activity ED50 is 0.1-0.5 ng/mL as determined by the ability of Recombinant CXCL7 to chemoattract human CXCR2 transfected BaF3 mouse proB cells. Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/μg (1 IEU/μg). Amino Acid Sequence AELRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQKKLAG DESADBackground Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). Similar to other ELR domain containing CXC chemokines, such as IL-8 and the GRO proteins, CXCL7 binds CXCR2, chemoattracts and activates neutrophils. CXCL7, Connective Tissue Activating Protein III (CTAPIII) and βthrombogulin (βTG), are proteolytically processed carboxylterminal fragments of platelet basic protein (PBP) which is found in the alphagranules of human platelets. Although CTAPIII, βTG, and PBP represent amino-terminal extended variants of NAP2 and possess the same CXC chemokine domains, these proteins do not exhibit CXCL7/NAP2 activity. CXCL7 induces cell migration through the G-protein-linked receptor CXCR-2.