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C275

Recombinant Human NAPA/Alpha-soluble NSF attachment protein

10ug

1200

1080

现货

国产

C275

Recombinant Human NAPA/Alpha-soluble NSF attachment protein

50ug

3520

3168

现货

国产

C275

Recombinant Human NAPA/Alpha-soluble NSF attachment protein

500ug

12320

11088

现货

国产

C275

Recombinant Human NAPA/Alpha-soluble NSF attachment protein

1mg

17600

15840

现货

国产

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  • Catalog# C275
    Source E.coli
    Description Recombinant Human α-Soluble NSF Attachment Protein/SNAP-α produced by E.coli expression system.Target protein is expressed with sequence (Met1-Arg295) of Human SNAPalpha (Uniprot #P54920) fused with a 6His tag at the N-terminus.
    Names Alpha-Soluble NSF Attachment Protein, SNAP-Alpha, N-Ethylmaleimide-Sensitive Factor Attachment Protein Alpha, NAPA, SNAPA
    Accession # P54920
    Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    MGSSHHHHHHSSGLVPRGSHMDNSGKEAEAMALLAEAERKVKNSQSFFSGLFGGSSKIEEACEIY ARAANMFKMAKNWSAAGNAFCQAAQLHLQLQSKHDAATCFVDAGNAFKKADPQEAINCLMRAIEI YTDMGRFTIAAKHHISIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAALL EQYQKAIDIYEQVGTNAMDSPLLKYSAKDYFFKAALCHFCIDMLNAKLAVQKYEELFPAFSDSRE CKLMKKLLEAHEEQNVDSYTESVKEYDSISRLDQWLTTMLLRIKKTIQGDEEDLR
    Background α-Soluble NSF Attachment Protein (SNAP-α) is a member of the SNAP (Soluble NSF Attachment Protein) family. SNAP-α interacts with PRKCABP and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. SNAP-α is required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. SNAP-α is in charge of the binding of NSF and therefore the formation of a 20S fusion particle.