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CG15

Recombinant Human CD337/NKp30/NCR3

10ug

1200

1080

现货

国产

CG15

Recombinant Human CD337/NKp30/NCR3

50ug

3520

3168

现货

国产

CG15

Recombinant Human CD337/NKp30/NCR3

500ug

13440

12096

现货

国产

CG15

Recombinant Human CD337/NKp30/NCR3

1mg

19200

17280

现货

国产

CG15

Recombinant Human NCR3/NKp30/NCR3/CD337(Fc fusion)

10ug

1200

1080

现货

国产

CG15

Recombinant Human NCR3/NKp30/NCR3/CD337(Fc fusion)

50ug

3520

3168

现货

国产

CG15

Recombinant Human NCR3/NKp30/NCR3/CD337(Fc fusion)

500ug

13440

12096

现货

国产

CG15

Recombinant Human NCR3/NKp30/NCR3/CD337(Fc fusion)

1mg

19200

17280

现货

国产

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  • Catalog# CG15
    Source HEK293
    Description Recombinant Human Natural Cytotoxicity Triggering Receptor 3/NCR3 is produced with our HEK293 expression system. The target protein is expressed with sequence (Leu19 -Thr138) of Human NCR3 fused with a FC tag at the C-terminus.
    Names Natural Cytotoxicity Triggering Receptor 3, Activating Natural Killer Receptor p30, Natural Killer Cell p30-Related Protein, NK-p30, NKp30, CD337, NCR3, 1C7, LY117
    Accession # O14931
    Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4
    Shipping The product is shipped at ambient temperature.
    Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in 1X PBS.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    LWVSQPPEIRTLEGSSAFLPCSFNASQGRLAIGSVTWFRDEVVPGKEVRNGTPEFRGRLAPLASS RFLHDHQAELHIRDVRGHDASIYVCRVEVLGLGVGTGNGTRLVVEKEHPQLGAGTVDDIEGRMDE PKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDG VEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREP QVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLT VDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    Background Natural Cytotoxicity Triggering Receptor 3 (NCR3) along with NKp44 and NKp46 constitute a group of receptors termed “Natural Cytotoxicity Receptors”. They play a major role in triggering NK-mediated killing of most tumor cells lines. NKp30 is a type I transmembrane protein having a single extracellular V-like immunoglobulin domain. NKp30 is selectively expressed both in resting and activated human NK cells. In addition, NKp30 is also involved in NK-mediated induction of dendritic cell (DC) maturation. It has been demonstrated that NK cell activation signaling specifically induces lytic activity against several tumor cell types and synthesis of new NF-κB dependent proteins during the initiation of cytotoxicity.