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C241

Recombinant Human Nucleoside diphosphate kinase A/NM23-H1/NDPKA

10ug

1200

1080

现货

国产

C241

Recombinant Human Nucleoside diphosphate kinase A/NM23-H1/NDPKA

50ug

3520

3168

现货

国产

C241

Recombinant Human Nucleoside diphosphate kinase A/NM23-H1/NDPKA

500ug

12320

11088

现货

国产

C241

Recombinant Human Nucleoside diphosphate kinase A/NM23-H1/NDPKA

1mg

17600

15840

现货

国产

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  • Catalog# C241
    Source E.coli
    Description Recombinant Human Nucleoside Diphosphate Kinase A/NDPKA is produced by our E. coli expression system. The target protein is expressed with sequence (Ala2-Glu152) of Human NDPKA fused with a His tag at the N-terminus.
    Names Nucleoside Diphosphate Kinase A, NDK A, NDP Kinase A, Granzyme A-Activated DNase, GAAD, Metastasis Inhibition Factor nm23, Tumor Metastatic Process-Associated Protein, nm23-H1, NME1, NDPKA, NM23
    Accession # P15531
    Formulation Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 10% Glycerol, pH 7.5
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/μg (1 IEU/μg).
    Amino Acid Sequence
    MGSSHHHHHHSSGLVPRGSHMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVGLKFMQASE DLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGETNPADSKPGTIRGDFCI QVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE
    Background Nucleoside-Diphosphate Kinases (NDKs) are enzymes that catalyze the exchange of phosphate groups between different nucleoside diphosphates. NDKs Possesse nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3-5 exonuclease activities. NDKs involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression and required for neural development including neural patterning and cell fate determination. Prokaryotic NDK forms a functional homotetramer.There are two isoforms of NDK in humans: NDK-A and NDK-B. Both have very similar structure, and can combine in any proportion to form functional NDK hexamers.