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CF68
Recombinant Human p50/POLD2/DNA polymerase delta subunit 2
10ug
1200
1080
现货
国产
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CF68
Recombinant Human p50/POLD2/DNA polymerase delta subunit 2
50ug
3520
3168
现货
国产
-
CF68
Recombinant Human p50/POLD2/DNA polymerase delta subunit 2
500ug
13440
12096
现货
国产
-
CF68
Recombinant Human p50/POLD2/DNA polymerase delta subunit 2
1mg
19200
17280
现货
国产
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Catalog# CF68 Source E.coli Description Recombinant Human DNA Polymerase Delta Subunit 2/POLD2 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Pro469) of Human POLD2 fused with a 6His tag at the C-terminus. Names DNA Polymerase Delta Subunit 2, DNA Polymerase Delta Subunit p50, POLD2 Accession # P49005 Formulation Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4 Shipping The product is shipped on dry ice/ice packs. Storage Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MFSEQAAQRAHTLLSPPSANNATFARVPVATYTNSSQPFRLGERSFSRQYAHIYATRLIQMRPFL ENRAQQHWGSGVGVKKLCELQPEEKCCVVGTLFKAMPLQPSILREVSEEHNLLPQPPRSKYIHPD DELVLEDELQRIKLKGTIDVSKLVTGTVLAVFGSVRDDGKFLVEDYCFADLAPQKPAPPLDTDRF VLLVSGLGLGGGGGESLLGTQLLVDVVTGQLGDEGEQCSAAHVSRVILAGNLLSHSTQSRDSINK AKYLTKKTQAASVEAVKMLDEILLQLSASVPVDVMPGEFDPTNYTLPQQPLHPCMFPLATAYSTL QLVTNPYQATIDGVRFLGTSGQNVSDIFRYSSMEDHLEILEWTLRVRHISPTAPDTLGCYPFYKT DPFIFPECPHVYFCGNTPSFGSKIIRGPEDQTVLLVTVPDFSATQTACLVNLRSLACQPISFSGF GAEDDDLGGLGLGPLEHHHHHHBackground DNA Polymerase Delta Subunit 2 (POLD2) belongs to the DNA polymerase delta/II small subunit family. POLD2 can form a heterotetramer composed of subunits of 125 kDa, 50 kDa, 66 kDa and 12 kDa. POLD2 possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. POLD2 is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA).