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CF62
Recombinant Human PDCD4/Programmed cell death protein 5
10ug
840
756
现货
国产
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CF62
Recombinant Human PDCD4/Programmed cell death protein 5
50ug
2520
2268
现货
国产
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CF62
Recombinant Human PDCD4/Programmed cell death protein 5
500ug
12320
11088
现货
国产
-
CF62
Recombinant Human PDCD4/Programmed cell death protein 5
1mg
17600
15840
现货
国产
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Catalog# CF62 Source E.coli Description Recombinant Human Programmed Cell Death Protein 4/PDCD4 is produced with our E. coli expression system. The target protein is expressed with sequence (Lys212-Pro357) of Human PDCD4 fused with a 6His tag at the C-terminus. Names Programmed Cell Death Protein 4, Neoplastic Transformation Inhibitor Protein, Nuclear Antigen H731-Like, Protein 197/15a, PDCD4, H731 Accession # Q53EL6 Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 Shipping The product is shipped at ambient temperature. Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in 1X PBS.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. Endotoxin Less than 0.1 ng/µg (1 IEU/µg). Amino Acid Sequence MKASHREMTSKLLSDLCGTVMSTTDVEKSFDKLLKDLPELALDTPRAPQLVGQFIARAVGDGILC NTYIDSYKGTVDCVQARAALDKATVLLSMSKGGKRKDSVWGSGGGQQSVNHLVKEIDMLLKEYLL SGDISEAEHCLKELEVPLEHHHHHHBackground Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation initiation and cap-dependent translation.PDCD4 promotes colonic neoplastic transformation and tumor invasion. PDCD4 is an important target for microrna R-21 in breast cancer cells. Shortage of PDCD4 expression is associated with colorectal cancer. Overexpression of PDCD4 in carcinoid cells results in inhibition of cell proliferation.