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CC92

Recombinant Human PDIA3/Protein disulfide-isomerase A3

10ug

1200

1080

现货

国产

CC92

Recombinant Human PDIA3/Protein disulfide-isomerase A3

50ug

3520

3168

现货

国产

CC92

Recombinant Human PDIA3/Protein disulfide-isomerase A3

500ug

13440

12096

现货

国产

CC92

Recombinant Human PDIA3/Protein disulfide-isomerase A3

1mg

19200

17280

现货

国产

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  • Catalog# CC92
    Source HEK293
    Description Recombinant Human Protein disulfide-isomerase A3/PDIA3 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ser25-Leu505) of Human PDIA3 fused with a polyhistidine tag at the C-terminus.
    Names PDIA3 protein is also known as Protein disulfide-isomerase A3.
    Accession # A5D7E8
    Formulation Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,10%Glycerol,pH7.5
    Shipping The product is shipped on dry ice/ice packs.
    Storage Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Purity Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
    Endotoxin Less than 0.1 ng/µg (1 IEU/µg).
    Amino Acid Sequence
    SDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANT NTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDA SIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKT VAYTEQKMTSGKIKKFIQENIFGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVM MVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKAL ERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEP KYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISY LQREATNPPVIQEEKPKKKKKAQEDLVDHHHHHH*
    Background PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.